Home Apoptosis -Immunology & Inflammation TNF-alpha TNF-αSelectief Inhibitors

TNF-αSelectief Inhibitors

Cat.nr. Productnaam Informatie Selectief / Pan IC50 / Ki
S4902 QNZ (EVP4593) QNZ (EVP4593) shows potent inhibitory activity toward both NF-κB activation and TNF-α production with IC50 of 11 nM and 7 nM, respectively. Selective TNF-α, IC50: 7 nM
S1029 Lenalidomide (CC-5013) Lenalidomide (CC-5013) is a TNF-α secretion inhibitor with IC50 of 13 nM. Selective TNF-α, IC50: 13 nM
S1567 Pomalidomide Pomalidomide inhibits LPS-induced TNF-α release with IC50 of 13 nM. Selective TNF-α, IC50: 13 nM
S8037 Necrostatin-1 Necrostatin-1 is a specific RIP1 inhibitor and inhibits TNF-α-induced necroptosis with EC50 of 490 nM. Selective RIP1, EC50: 490 nM
S1193 Thalidomide Thalidomide was introduced as a sedative drug, immunomodulatory agent and also is investigated for treating symptoms of many cancers. Thalidomide inhibits an E3 ubiquitin ligase, which is a CRBN-DDB1-Cul4A complex. Selective