Cat.nr.L3500
Een unieke collectie van 590 gevalideerde, zeer selectieve remmers die meer dan 123 doelwitten bestrijken.
Geciteerd door 337 Publicaties
• A unique collection of 590 validated highly selective inhibitors with covering over 123 targets
• Selectivity is at least 100-fold higher relative to non-primary target(s)
• Each compound was selected based on its ability to principally interact with a single target, leading to minimal off-target activity
•Targets cover a wide variety of signaling pathways, including PI3K/Akt, MAPK, PTK, JAK, apoptosis, and others!
• This unique tool is ideal for studying mechanisms of action or for target screening
• Compounds are structurally diverse, biologically active, and cell permeable
• Selleck provides rich supporting documentation which includes compound structure and customer reviews
• Compounds are NMR and HPLC validated to ensure our customers receive high purity compounds
| Formulering | 555 compounds pre-dissolved in 10mM DMSO, 9 compounds pre-dissolved in 10mM water and 26 compounds pre-dissolved in 2mM DMSO | ||
|---|---|---|---|
| Container | 96 Deep Well Plaat verzegeld met aluminiumfolie | ||
| Stabiliteit | 12 months | -20°C | in DMSO |
| 24 months | -80°C | in DMSO | |
| Verzending | Koude elementen of droogijs | ||
Toepassing van GPCR Compound Library bij leverkanker (Dit artikel is gepubliceerd in Nature (IF
Toepassing van Kinase Inhibitor Library bij darmkanker (Dit artikel is gepubliceerd in Nature Communications (IF
Toepassing van FDA-approved Drug Library bij antivirus (Dit artikel is gepubliceerd in Cell Research (IF
Toepassing van FDA-approved Drug Library in metabolisme (Dit artikel is gepubliceerd in Movement Disorders (IF
Toepassing van Epigenetics Compound Library bij acute lymfatische leukemie (Dit artikel is gepubliceerd in Blood (IF
Toepassing van Inhibitor Library in tumorimmunologie (Dit artikel is gepubliceerd in Cancer Immunol Res (IF