Highly Selective Inhibitor Library

Cat.nr.L3500

Een unieke collectie van 590 gevalideerde, zeer selectieve remmers die meer dan 123 doelwitten bestrijken.

96 well plates

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Geciteerd door 337 Publicaties

Beschrijving en voordelen

• A unique collection of 590 validated highly selective inhibitors with covering over 123 targets

• Selectivity is at least 100-fold higher relative to non-primary target(s)

• Each compound was selected based on its ability to principally interact with a single target, leading to minimal off-target activity

•Targets cover a wide variety of signaling pathways, including PI3K/Akt, MAPK, PTK, JAK, apoptosis, and others!

• This unique tool is ideal for studying mechanisms of action or for target screening

• Compounds are structurally diverse, biologically active, and cell permeable

• Selleck provides rich supporting documentation which includes compound structure and customer reviews

• Compounds are NMR and HPLC validated to ensure our customers receive high purity compounds

Productdetails

Formulering 555 compounds pre-dissolved in 10mM DMSO, 9 compounds pre-dissolved in 10mM water and 26 compounds pre-dissolved in 2mM DMSO
Container 96 Deep Well Plaat verzegeld met aluminiumfolie
Stabiliteit 12 months -20°C in DMSO
24 months -80°C in DMSO
Verzending Koude elementen of droogijs

Casestudies met Selleck Compound Libraries

Highly Selective Inhibitor Library Samenstelling

HTS Faciliteit Partners

  • Collaborating with Seleck: Yale University | Yale Center for Molecular Discovery
  • Collaborating with Seleck: Carbone Cancer Center | University of Wisconsin-Madison
  • Collaborating with Seleck: University of Colorado Denver | CU Denver
  • Collaborating with Seleck: Leibniz-Forschungsinstitut für Molekulare Pharmakologie: Leibniz-FMP
  • Collaborating with Seleck: UCSF_University of California San Francisco
  • Collaborating with Seleck: KU | High Throughput Screening Laboratory
  • Collaborating with Seleck: CIBIO
  • Collaborating with Seleck: Perelman school of medicine | University of Pennsylvania