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GPCR Compound Library

Cat.nr.L2200

Een unieke collectie van 1417 kleine moleculen gericht op G-proteïnegekoppelde receptoren voor high-throughput screening (HTS) en high-content screening (HCS).

96 well plates

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Beschrijving en voordelen

•A unique collection of 1417 small molecules targeting G protein coupled receptors for high throughput screening (HTS) and high content screening (HCS)
• All of the small molecules in the GPCR library are well characterized with biological and pharmaceutical activity
• A powerful tool for discovering GPCR-based drugs that are the richest signal receptor targets for drug discovery
• It is estimated about 200 so-called orphan GPCRs are functionally unknown, as a result, use of our GPCR Small Molecule Compound Library for screening the functionally unknown GPCRs may yield potentially new GPCR-based drug candidates
• The GPCR compound library contains small molecules associated with receptors including 5-HT Receptor, Dopamine Receptor, Opioid Receptor, Adrenergic Receptors, Cannabinoid Receptor, mGluR, and ETA-receptor etc.
• Structurally diverse, medicinally active, and cell permeable
• Rich documentation with structure and customer reviews
• NMR and HPLC validated to ensure the highest purity

Productdetails

Formulering 1299 compounds pre-dissolved in 10mM DMSO, 76 compounds pre-dissolved in 10mM water, 37 compounds pre-dissolved in 2mM DMSO and 5 compounds pre-dissolved in 2mM water
Container 96 Deep Well Plaat verzegeld met aluminiumfolie
Stabiliteit 12 months -20°C in DMSO
24 months -80°C in DMSO
Verzending Koude elementen of droogijs

Casestudies met Selleck Compound Libraries

GPCR Compound Library Samenstelling

HTS Faciliteit Partners

  • Collaborating with Seleck: Yale University | Yale Center for Molecular Discovery
  • Collaborating with Seleck: Carbone Cancer Center | University of Wisconsin-Madison
  • Collaborating with Seleck: University of Colorado Denver | CU Denver
  • Collaborating with Seleck: Leibniz-Forschungsinstitut für Molekulare Pharmakologie: Leibniz-FMP
  • Collaborating with Seleck: UCSF_University of California San Francisco
  • Collaborating with Seleck: KU | High Throughput Screening Laboratory
  • Collaborating with Seleck: CIBIO
  • Collaborating with Seleck: Perelman school of medicine | University of Pennsylvania